Dr Larissa Balakireva, CEO & Founder of NovoCIB, was awarded with the Trophy of
"Femmes en Or 2011, Femme de l'Innovation"
in September 2011

Nucleotides - Life Science

A nucleotide is a biochemical compound made of three components: a nitrogen-containing base, a ribose, and one or more phosphate groups. Nucleotides participate in nearly all biochemical processes. Adenosine triphosphate (ATP) is a universal energy currency in all biological systems and is particularly abundant in muscles where it is used for contraction. Adenine nucleotides are components of three major coenzymes, NAD+, FAD, and CoA. Cyclic AMP is a ubiquitous second messenger used for intracellular signal transduction in different organisms.

Being building blocks of nucleic acids (DNA and RNA), nucleotides are essential for proliferation of all living organisms from viruses to high eucaryotes. The needs of proliferating cells in nucleotides can be met through de novo synthesis of nucleotides or by salvage pathway.

The inborn defects in genes coding for the enzymes of nucleotides biosynthesis or salvage are known to result in severe immunological and neurological syndroms.

Targeting the enzymes of nucleotides biosynthesis is a recognized strategy for chemotherapy of cancer and anti-viral treatment.

NOVOCIB offers a range of original enzymatic assays and and analytical services

1) For non-radioactive detection of several purine metabolism disorders

2) For Drug Discovery of novel inhibitors of nucleotide biosynthesis

Know more about NOVOCIB Assay Kits

Know more about HPLC Analysis

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