Using ion-paired high-performance liquid chromatography with diode array detection NOVOCIB provides HPLC analytical services of full spectra of nucleotides in cell extracts and in feed/ food products and ingredients.
Quality Control of Yeast Extract Nucleotides: NOVOCIB offers a range of analytical services from characterization of free 5' nucleotides to full spectrum of nucleotides in yeast extracts by ion-pair high-performance liquid chromatography with diode array detection. This service allows to control the content of flavor nucleotides yeast extract samples.
Cellular Nucleotide Profiling Service is an analytical service for measuring nucleotide level in antimetabolite-treated cells. More than 31 cellular (deoxy-) ribonucleotides (mono-, di-, and triphosphate) are extracted by SPE procedure, separated by ion-paired HPLC system in one-run and quantified.
Nucleotides participate in nearly all biochemical processes important for growth: ATP is an universal energy currency in all biological systems particularly abundant in muscles. Adenine nucleotides are components of three major coenzymes, NAD+, FAD, and CoA. Being building blocks of the nucleic acids (DNA and RNA), nucleotides are particularly required for actively proliferating cells of the immune system or intestinal epithelium.