Taste-Enhancing Nucleotides

Taste-potentiating nucleotides—including inosine monophosphate (IMP, inosinic acid and its salts E630-E633), guanosine monophosphate (GMP, guanylic acid and its salts E626-E629), and adenosine monophosphate (AMP, E629)—play a pivotal role in enhancing umami perception through synergistic interactions with glutamate.

IMP is naturally present in the muscle tissues of animals, particularly in fresh seafood, chicken, pork, and beef and is a key contributor to the umami flavor.

GMP, AMP, and IMP can also be produced via microbial fermentation using yeasts or specific bacterial strains such as Corynebacterium and Bacillus. These nucleotides are commonly used as food additives in processed products such as soups, snacks, sauces, and instant noodles to intensify savory flavor profiles and elevate overall taste experience.

NOVOCIB provides:

  1. analytical service for the determination of full spectra of nucleotides in food and feed using HPLC-UV.;
  2. PRECICE® enzymatic assay kits for nucleotides determination in fishmeal, yeast extracts and related products:

Available Assay Kits

PRECICE® Fishmeal IMP Assay kit

For the quantitative determination of Inosine Monophosphate (IMP) in various samples.

  • Sensitivity: 0.1 µM
  • Range: 0.2-50 µM
  • Sample Type: Food, biological fluids

PRECICE® GMP-IMP Assay kit

For the quantitative determination of Guanosine Monophosphate (GMP).

  • Sensitivity: 0.15 µM
  • Range: 0.3-60 µM
  • Sample Type: Food, biological samples

Yeast Extract IMP-AMP Assay kit

For the quantitative determination of Adenosine Monophosphate (AMP).

  • Sensitivity: 0.2 µM
  • Range: 0.5-100 µM
  • Sample Type: Biological fluids, tissue extracts

PRECICE® Nucleotides Kits

PRECICE® Nucleotides kits have been developed in a user-friendly 96-well format.

Microplates provided with the kit are prefilled:

  • With the enzymes that simplify the assay procedure
  • With calibration standards

Advantages of Using PRECICE® Nucleotides Kits

  • Enzymes are stereospecific towards 5'NMP
  • Enzymatic approach is faster than analytical approach
  • Ecologic (no solvent, extraction by boiling)
  • Time and cost-efficient

Features & Benefits

Technical Support

Our technical support team is available to assist with any questions regarding our Nucleotides Assay Kits. Please contact our technical support for protocol optimization, troubleshooting, and application-specific advice.

Contact Us for More Information