Feed supplementation with nucleotides
Nucleotides participate in nearly all biochemical processes:
Nucleotides | Cellular function |
Biological role |
---|---|---|
ATP | Actine-myosin interaction |
Muscle contraction |
NTP | RNA synthesis (translation) |
Protein synthesis |
dNTP | DNA synthesis (replication) |
Proliferation |
NAD, FAD | Redox reactions |
Metabolism |
Coenzyme A | Krebs cycle |
Fatty acids metabolism |
UDP-glucose | Neoglycogenesis
|
Liver functions, muscle growth |
Being building blocks of the nucleic acids (DNA and RNA), nucleotides are particularly required for actively proliferating cells of immune system or intestinal epithelium. Nucleotides added to animal feed are rapidly assimilated through salvage pathway and accelerates RNA and DNA synthesis, and as a consequence :
- boosts immune system, enhances immunity and resistance to bacterial infections.;
- accelerates intestinal recovery after diarrhoea or food deprivation;
- improves growth rate.
NOVOCIB assists the development of new feed ingredients providing
1) Enzymatic Assay Kit for rapid assessment of purine nucleotides IMP, inosine and hypoxanthine in aquaculture feed;
2) Analytical service of nucleotide assessement in feed and in feed ingredients.